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LBL06001: Difference between revisions
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'''3. Responsibilities''' | '''3. Responsibilities''' | ||
Ultimately the laboratory user who initiates and undertakes the lab work (aka The Principal Investigator) is responsible for the health and safety considerations and containment requirements involved with their project. It is a requirement that they be aware of the risks involved in the project and the exposure to these risks by themselves, other lab users, the wider community and the environment. | Ultimately, the laboratory user who initiates and undertakes the lab work (aka The Principal Investigator) is responsible for the health and safety considerations and containment requirements involved with their project. It is a requirement that they be aware of the risks involved in the project and the exposure to these risks by themselves, other lab users, the wider community and the environment. | ||
Before commencing any work the risks involved in the project must be assessed by the the principal investigator, they must seek advice from an experienced third party and the satisfactory results of this process must be signed off by the Biological Safety Officer. | Before commencing any work the risks involved in the project must be assessed by the the principal investigator, they must seek advice from an experienced third party and the satisfactory results of this process must be signed off by the Biological Safety Officer. | ||
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'''6. Definitions''' | '''6. Definitions''' | ||
GMM<br> | GMM - Genetically Modified Microorganism<br> | ||
GMO<br> | GMO - Genetically Modified Organism<br> | ||
COSHH<br> | COSHH - Control of Substances Hazardous to Health<br> | ||
SOP<br> | SOP - Standard Operating Procedure<br> | ||
HG<br> | HG - Hazard Group<br> | ||
CL<br> | CL - Containment Level<br> | ||
PI<br> | PI - Principal Investigator<br> | ||
PPE<br> | PPE - Personal Protective Equipment<br> | ||
MSDS - Material Safety Data Sheet<br> | |||
'''7. Procedures''' | '''7. Procedures''' | ||
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7.1.7.2 The PI should also consider the potential for transfer of genetic material between the GM plant and other organisms. | 7.1.7.2 The PI should also consider the potential for transfer of genetic material between the GM plant and other organisms. | ||
7.2 Asessing the risks involved in the use of chemicals and reagents. | |||
7.2.1 The principal investigator should check whether a required chemical or reagent for their project is already in use in the laboratory. | |||
If not they should locate the relavent MSDS for the substance in question and should pay particular attention to the following factors: | |||
i) How should the substance be handled? Is particular PPE required, and is this available? | |||
ii) How is the substance stored and can this be accommodated in the laboratory? For example, it may not be practical to store highly | |||
volatile, flammable, corrosive or controlled substances on site. | |||
iii) How should the substance be disposed of? Primarily, can this be disposed of down the drain (diluted or undiluted?) or are special | |||
disposal measures required? If so are these available? | |||
7.3 Assessing the risks involved in the use of instrumentation and equipment | |||
7.3.1 The principal investigator should assess any risk presented by instrumentation or equipment brought into the lab for the purpose of | |||
carrying out this project. | |||
Some examples might be: does it operate at high temperature or pressure, produce wavelengths of light that might be harmful (i.e uses | |||
lasers or UV bulbs), does it operate at high voltages (e.g electroporator),produce high frequency sounds that might be damaging to | |||
hearing (e.g sonicators) or might be heavy or awkward to operate. | |||
7.3.2 The principal investigator should check the SOP documentation for information covering similar devices, and the information covering the | |||
laboratory safety induction which should cover most of the installed devices at the time of writing. | |||
'''8. Resources''' | '''8. Resources''' | ||
